Scalable and Sustainable Dry Microfabrication Enabled by High-Precision and Wafer-Scale Transfer Lithography of Commercial Photoresists
Corresponding Author: Yunda Wang
Nano-Micro Letters,
Vol. 18 (2026), Article Number: 357
Abstract
Conventional photolithography is inherently limited to flat, rigid, and stable substrates, which severely restricts its applicability to flexible, curved, and transient electronic devices. This work presents an innovative transfer method that exploits a phase-changing polymer with dynamically switchable adhesion to enable universal transfer of commercial photoresists onto a broad range of previously incompatible substrates, thereby overcoming the fundamental limitations of traditional photolithography. Remarkably, this method achieves reliable wafer-scale (~ 4-inch) transfer with a global registration error below 60 µm, unlocking high-fidelity patterning on challenging surfaces such as solvent-sensitive, curved, microtextured, or fragile substrates. Combined with dry etching, this study demonstrates a new route for high-resolution patterning of delicate functional materials, including quantum dots and organic semiconductors. Moreover, it supports a sustainable “dry lift-off” process for patterning functional layers, demonstrating a successful high-resolution microfabrication on paper-based substrate. The reusability of both the transfer carrier and photoresist markedly enhances process sustainability and scalability, representing a significant advance in microfabrication. This unprecedented capability is further demonstrated by fabricating a micro-sized UV photodetector array featuring wide-angle sensing capability on a curved glass bottle.
Highlights:
1 Universal, high-precision and wafer-scale (~ 4-inch) transfer lithography of multiple commercial photoresists for patterning various lithography-incompatible substrates.
2 A novel route for etching-enabled high-resolution patterning of susceptible materials (e.g., quantum dots and organic semiconductors).
3 A sustainable “dry lift-off” for functional material patterning and advanced device manufacturing (e.g., paper-based electronics and curved electronics).
Keywords
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References
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S. Aziz, K.G. Bum, Y.J. Yang, B.-S. Yang, C.U. Kang et al., Fabrication of ZnSnO3 based humidity sensor onto arbitrary substrates by micro-nano scale transfer printing. Sens. Actuators A Phys. 246, 1–8 (2016). https://doi.org/10.1016/j.sna.2016.04.059
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Z. Li, S. Chu, Y. Zhang, W. Chen, J. Chen et al., Mass transfer printing of metal-halide perovskite films and nanostructures. Adv. Mater. 34(35), 2203529 (2022). https://doi.org/10.1002/adma.202203529
G. Liu, Z. Tian, Z. Yang, Z. Xue, M. Zhang et al., Graphene-assisted metal transfer printing for wafer-scale integration of metal electrodes and two-dimensional materials. Nat. Electron. 5(5), 275–280 (2022). https://doi.org/10.1038/s41928-022-00764-4
J. Yoo, K. Lee, U.J. Yang, H.H. Song, J.H. Jang et al., Highly efficient printed quantum dot light-emitting diodes through ultrahigh-definition double-layer transfer printing. Nat. Photonics 18(10), 1105–1112 (2024). https://doi.org/10.1038/s41566-024-01496-x
G. Zabow, Reflow transfer for conformal three-dimensional microprinting. Science 378(6622), 894–898 (2022). https://doi.org/10.1126/science.add7023
J. Yeom, M.A. Shannon, Detachment lithography of photosensitive polymers: a route to fabricating three-dimensional structures. Adv. Funct. Mater. 20(2), 289–295 (2010). https://doi.org/10.1002/adfm.200900686
Z. Shu, B. Feng, P. Liu, L. Chen, H. Liang et al., Near-zero-adhesion-enabled intact wafer-scale resist-transfer printing for high-fidelity nanofabrication on arbitrary substrates. Int. J. Extreme Manuf. 6(1), 015102 (2024). https://doi.org/10.1088/2631-7990/ad01fe
Y. Zhou, L. Chen, Z. Shu, F. Fan, Y. Hu et al., Wafer-level perfect conformal contact lithography at the diffraction limit enabled by dry transferable photoresist. Int. J. Extreme Manuf. 7(6), 065101 (2025). https://doi.org/10.1088/2631-7990/adf60f
L. Chen, H. Liang, P. Liu, C. Liu, B. Feng et al., Sustainable lithography paradigm enabled by mechanically peelable resists. Adv. Mater. 37(3), e2410978 (2025). https://doi.org/10.1002/adma.202410978
Y. Zhou, B. Feng, L. Chen, F. Fan, Z. Ji et al., Wafer-recyclable, eco-friendly, and multiscale dry transfer printing by transferable photoresist for flexible epidermal electronics. ACS Appl. Mater. Interfaces 16(11), 13525–13533 (2024). https://doi.org/10.1021/acsami.3c18576
Q. Liu, Y. Chen, Z. Feng, Z. Shu, H. Duan, Resist nanokirigami for multipurpose patterning. Natl. Sci. Rev. 9(11), nwab231 (2022). https://doi.org/10.1093/nsr/nwab231
J.D. Eisenhaure, S.I. Rhee, A.M. Al-Okaily, A. Carlson, P.M. Ferreira et al., The use of shape memory polymers for microassembly by transfer printing. J. Microelectromech. Syst. 23(5), 1012–1014 (2014). https://doi.org/10.1109/JMEMS.2014.2345274
J.D. Eisenhaure, S.I. Rhee, A.M. Al-Okaily, A. Carlson, P.M. Ferreira et al., The use of shape memory polymers for MEMS assembly. J. Microelectromech. Syst. 25(1), 69–77 (2016). https://doi.org/10.1109/JMEMS.2015.2482361
Z. Ren, W. Hu, C. Liu, S. Li, X. Niu et al., Phase-changing bistable electroactive polymer exhibiting sharp rigid-to-rubbery transition. Macromolecules 49(1), 134–140 (2016). https://doi.org/10.1021/acs.macromol.5b02382
Q. Guo, J. Zhang, X. Shu, J. Zhang and Q. Chen et al., Micro-transfer printing of photoresist using adhesion- switchable stamp for patterning unconventional surface. In 2024 IEEE 37th International Conference on Micro Electro Mechanical Systems (MEMS), (IEEE, 2024), pp. 669–672. https://doi.org/10.1109/MEMS58180.2024.10439425
J. Zhang, X. Shu, Q. Guo, D. Lu and Y. Wang, A sharp phase transition shape memory polymer for micro-transfer printing. In 2024 IEEE 19th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS), (IEEE, 2024), pp. 1–4. https://doi.org/10.1109/NEMS60219.2024.10639896
M.D. Bartlett, A.B. Croll, D.R. King, B.M. Paret, D.J. Irschick et al., Looking beyond fibrillar features to scale gecko-like adhesion. Adv. Mater. 24(8), 1078–1083 (2012). https://doi.org/10.1002/adma.201104191
J. Schindelin, I. Arganda-Carreras, E. Frise, V. Kaynig, M. Longair et al., Fiji: an open-source platform for biological-image analysis. Nat. Methods 9(7), 676–682 (2012). https://doi.org/10.1038/nmeth.2019
D.G. Lowe, Distinctive image features from scale-invariant keypoints. Int. J. Comput. Vis. 60(2), 91–110 (2004). https://doi.org/10.1023/B:VISI.0000029664.99615.94
H. Wu, Y. Tian, H. Luo, H. Zhu, Y. Duan et al., Fabrication techniques for curved electronics on arbitrary surfaces. Adv. Mater. Technol. 5(8), 2000093 (2020). https://doi.org/10.1002/admt.202000093
J.-H. Kim, Q. Zhou and J. Chang, A facile dry-PMMA transfer process for electron-beam lithography on non-flat substrates. In 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems (MEMS), (IEEE, 2017), pp. 274–277. https://doi.org/10.1109/MEMSYS.2017.7863394
D. Chen, H. Tan, T. Xu, W. Wang, H. Chen et al., Micropatterned PEDOT with enhanced electrochromism and electrochemical tunable diffraction. ACS Appl. Mater. Interfaces 13(48), 58011–58018 (2021). https://doi.org/10.1021/acsami.1c17897
H. Liang, Z. Shu, Y. Jiang, M. Liu, Q. Wang et al., Reliable fabrication of nanoscale Cr patterns with dry lift-off process for hard mask applications in microelectronics. Microelectron. Eng. 301, 112396 (2026). https://doi.org/10.1016/j.mee.2025.112396
B.J. Kim, B. Shao, A.T. Hoang, S. Yun, J. Hong et al., A flexible active-matrix X-ray detector with a backplane based on two-dimensional materials. Nat. Electron. 8(2), 147–156 (2025). https://doi.org/10.1038/s41928-024-01317-7
X. Feng, M.A. Meitl, A.M. Bowen, Y. Huang, R.G. Nuzzo et al., Competing fracture in kinetically controlled transfer printing. Langmuir 23(25), 12555–12560 (2007). https://doi.org/10.1021/la701555n
J. Kim, S. Kim, T. Yun, J.H. Kim, C. Son et al., Shape memory polymer surfaces with controllable roughness for multiscale switchable dry adhesion. Nat. Commun. 16, 4954 (2025). https://doi.org/10.1038/s41467-025-60220-7