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Vol. 6 No. 2 (2014)

A Novel Photothermal Nanocrystals of Cu7S4 Hollow Structure for Efficient Ablation of Cancer Cells

https://doi.org/10.1007/BF03353781
Guosheng Song
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China
Linbo Han
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China
Weiwei Zou
Radiology Departments, Changzheng Hospital, Shanghai 200003, China
Zhiyin Xiao
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China
XiaoJuan Huang
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China
Zongyi Qin
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China
Rujia Zou
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China
Junqing Hu
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China

Corresponding Author: Junqing Hu

hu.junqing@dhu.edu.cn

Nano-Micro Letters, Vol. 6 No. 2 (2014), Article Number: 169-177

Abstract

Cu2-xS nanocrystals (NCs), characterized by low cost, low toxicity, high stability and high photothermal conversion efficiency, provide promising platforms as photothermal agents. Herein, a novel two-step synthesis has been developed for Cu7S4 nanocrystals with hollow structure using the as-prepared copper nanoparticles as starting a solid precursor followed by hot-injection of sulfide source.The Cu7S4 NCs exhibit intense absorption band at Near-infrared (NIR) wavelengths due to localized surface plasmon resonance (LSPR) mode, which can effectively convert 980 nm-laser energy into heat.Moreover, the localized high temperature created by Cu7S4 NCs under NIR irradiation could result in efficient photothermal ablation (PTA) of cancer cells in vivo, demonstrating a novel and promising photothermal nanomaterials.

Keywords

Semiconductor nanocrystals Near-infrared absorption Photothermal
Song, Guosheng, Linbo Han, Weiwei Zou, Zhiyin Xiao, XiaoJuan Huang, Zongyi Qin, Rujia Zou, and Junqing Hu. 2014. “A Novel Photothermal Nanocrystals of Cu7S4 Hollow Structure for Efficient Ablation of Cancer Cells”. Nano-Micro Letters 6 (2):169-77. https://doi.org/10.1007/BF03353781.
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References
  1. J. Yu, D. Javier, M. A. Yaseen, N. Nitin, R. Richards-Kortum, B. Anvari and M. S. Wong, “Selfassembly synthesis, tumor cell targeting, and photothermal capabilities of antibody-coated indocyanine green nanocapsules”, J. Am. Chem. Soc. 132(6), 1929–1938 (2010). http://dx.doi.org/10.1021/ja908139y
  2. J. Yang, J. Choi, D. Bang, E. Kim, E. K. Lim, H. Park, J. S. Suh, K. Lee, K. H. Yoo, E. K. Kim, Y. M. Huh and S. Haam, “Convertible organic nanoparticles for near-infrared photothermal ablation of cancer cells”, Angew. Chem. Int. Ed. 50(2), 441–444 (2011). http://dx.doi.org/10.1002/anie.201005075
  3. X. Wang, C. Wang, L. Cheng, S.-T. Lee and Z. Liu, “Noble metal coated single-walled carbon nanotubes for applications in surface enhanced raman scattering imaging and photothermal therapy”, J. Am. Chem. Soc. 134(17), 7414–7422 (2012). http://dx.doi.org/10.1021/ja300140c
  4. V. S. Thakare, M. Das, A. K. Jain, S. Patil and S. Jain, “Carbon nanotubes in cancer theragnosis”, Nanomedicine 5(8), 1277–1301 (2010). http://dx.doi.org/10.2217/nnm.10.95
  5. F. Zhou, S. Wu, S. Song, W. R. Chen, D. E. Resasco and D. Xing, “Antitumor immunologically modified carbon nanotubes for photothermal therapy”, Biomaterials 33(11), 3235–3242 (2012). http://dx.doi.org/10.1016/j.biomaterials.2011.12.029
  6. J. T. Robinson, S. M. Tabakman, Y. Liang, H. Wang, H. S. Casalongue, V. Daniel and H. Dai, “Ultrasmall reduced graphene oxide with high near-infrared absorbance for photothermal therapy”, J. Am. Chem. Soc. 133(17), 6825–6831 (2011). http://dx.doi.org/10.1021/ja2010175
  7. M. Li, X. Yang, J. Ren, K. Qu and X. Qu, “Using graphene oxide high near-infrared absorbance for photothermal treatment of alzheimer’s disease”, Adv. Mater. 24(13), 1722–1728 (2012). http://dx.doi.org/10.1002/adma.201104864
  8. K. Yang, L. Hu, X. Ma, S. Ye, L. Cheng, X. Shi, C. Li, Y. Li and Z. Liu, “Multimodal imaging guided photothermal therapy using functionalized graphene nanosheets anchored with magnetic nanoparticles”, Adv. Mater. 24(14), 1868–1872 (2012). http://dx.doi.org/10.1002/adma.201104964
  9. K. Yang, J. Wan, S. Zhang, B. Tian, Y. Zhang and Z. Liu, “The influence of surface chemistry and size of nanoscale graphene oxide on photothermal therapy of cancer using ultra-low laser power”, Biomaterials. 33(7), 2206–2214 (2012). http://dx.doi.org/10.1016/j.biomaterials.2011.11.064
  10. B. Jang, J. Y. Park, C. H. Tung, I. H. Kim and Y. Choi, “Gold nanorod-photosensitizer complex for near-infrared fluorescence imaging and photodynamic/photothermal therapy in vivo”, ACS Nano. 5(2), 1086–1094 (2011). http://dx.doi.org/10.1021/nn102722z
  11. C. G. Wang, J. Chen, T. Talavage and J. Irudayaraj, “Gold nanorod/Fe3O4nanoparticle nano-pearlnecklaces for simultaneous targeting, dual-mode imaging, and photothermal ablation of cancer cells”, Angew. Chem. Int. Ed. 48(15), 2759–2763 (2009). http://dx.doi.org/10.1002/anie.200805282
  12. Z. Zhang, L. Wang, J. Wang, X. Jiang, X. Li, Z. Hu, Y. Ji, X. Wu and C. Chen, “Mesoporous silicacoated gold nanorods as a light-mediated multifunctional theranostic platform for cancer treatment”, Adv. Mater. 24(11), 1418–1423 (2012). http://dx.doi.org/10.1002/adma.201104714
  13. H. Liu, T. Liu, X. Wu, L. Li, L. Tan, D. Chen and F. Tang, “Targeting gold nanoshells on silica nanorattles: a drug cocktail to fight breast tumors via a single irradiation with near-infrared laser light”, Adv. Mater. 24(6), 755–761 (2012). http://dx.doi.org/10.1002/adma.201103343
  14. H. Liu, D. Chen, L. Li, T. Liu, L. Tan, X. Wu and F. Tang, “Multifunctional gold nanoshells on silica nanorattles: aplatform for the combination of photothermal therapy and chemotherapy with low systemic toxicity”, Angew. Chem. Int. Ed. 50(4), 891–895 (2011). http://dx.doi.org/10.1002/anie.201002820
  15. Y. Xia, W. Li, C. M. Cobley, J. Chen, X. Xia, Q. Zhang, M. Yang, E. C. Cho and P. K. Brown, “Gold nanocages: from synthesis to theranostic applications”, Acc. Chem. Res. 44(10), 914–924 (2011). http://dx.doi.org/10.1021/ar200061q
  16. J. Chen, C. Glaus, R. Laforest, Q. Zhang, M. Yang, M. Gidding, M. J. Welch and Y. Xia, “Gold nanocages as photothermal transducers for cancer treatment”, Small 6(7), 811–817 (2010). http://dx.doi.org/10.1002/smll.200902216
  17. H. Yuan, A. M. Fales and T. Vo-Dinh, “TAT peptidefunctionalized gold nanostars: enhanced intracellular delivery and efficient NIR photothermal therapy using ultralow irradiance”, J. Am. Chem. Soc. 134 (28), 11358–11361 (2012). http://dx.doi.org/10.1021/ja304180y
  18. X. Q. Huang, S. H. Tang, X. L. Mu, Y. Dai, G. X. Chen, Z. Y. Zhou, F. X. Ruan, Z. L. Yang and N. F. Zheng, “Freestanding palladium nanosheets with plasmonic and catalytic properties”, Nat. Nanotechnol.. 6(1), 28–32 (2011). http://dx.doi.org/10.1038/nnano.2010.235
  19. Q. Tian, F. Jiang, R. Zou, Q. Liu, Z. Chen, M. Zhu, S. Yang, J. Wang, J. Wang and J. Hu, “Hydrophilic Cu9S5nanocrystals: aphotothermal agent with a 25.7% heat conversion efficiency for photothermal ablation of cancer cells in vivo”, ACS Nano 5(12), 9761–9771 (2011). http://dx.doi.org/10.1021/nn203293t
  20. G. Song, Q. Wang, Y. Wang, G. Lv, C. Li, R. Zou, Z. Chen, Z. Qin, K. Huo, R. Hu and J. Hu, “A low-toxic multifunctional nanoplatform based on Cu9S5@mSiO2core-shell nanocomposites: combining photothermal- and chemotherapies with infrared thermal imaging for cancer treatment”, Adv. Funct. Mater. 23(35), 4281–4292 (2013). http://dx.doi.org/10.1002/adfm.201203317
  21. Q. Tian, M. Tang, Y. Sun, R. Zou, Z. Chen, M. Zhu, S. Yang, J. Wang, J. Wang and J. Hu, “Hydrophilic flower-like CuS superstructures as an efficient 980 nm laser-driven photothermal agent for ablation of cancer cells”, Adv. Mater. 23(31), 3542–3547 (2011). http://dx.doi.org/10.1002/adma.201101295
  22. Q. Tian, J. Hu, Y. Zhu, R. Zou, Z. Chen, S. Yang, R. Li, Q. Su, Y. Han and X. Liu, “Sub-10 nm Fe3O4@Cu2-xS core-shell nanoparticles for dualmodal imaging and photothermal therapy”, J. Am. Chem. Soc. 135(23), 8571–8577 (2013). http://dx.doi.org/10.1021/ja4013497
  23. C. M. Hessel, V. P. Pattani, M. Rasch, M. G. Panthani, B. Koo, J. W. Tunnell and B. A. Korgel, “Copper selenide nanocrystals for photothermal therapy”, Nano Lett. 11(6), 2560–2566 (2011). http://dx.doi.org/10.1021/nl201400z
  24. M. Zhou, R. Zhang, M. A. Huang, W. Lu, S. L. Song, M. P. Melancon, M. Tian, D. Liang and C. Li, “A chelator-free multifunctional [64Cu]CuS nanoparticle platform for simultaneous micro-PET/CT imaging and photothermal ablation therapy”, J. Am. Chem. Soc. 132(43), 15351–15358 (2010). http://dx.doi.org/10.1021/ja106855m
  25. M. Shi, H. S. Kwon, Z. Peng, A. Elder and H. Yang, “Effects of surface chemistry on the generation of reactive oxygen species by copper nanoparticles”, ACS Nano. 6(3), 2157–2164 (2012). http://dx.doi.org/10.1021/nn300445d
  26. Y. Yin, R. M. Rioux, C. K. Erdonmez, S. Hughes, G. A. Somorjai and A. P. Alivisatos, “Formation of hollow nanocrystals through the nanoscale Kirkendall effect”, Science 304, 711–714 (2004). http://dx.doi.org/10.1126/science.1096566
  27. W. Li, A. Shavel, R. Guzman, J. Rubio-Garcia, C. Flox, J. Fan, D. Cadavid, M. Ibá≈nez, J. Arbiol, J. R. Morante and A. Cabot, “Morphology evolution of Cu2-xS nanoparticles: from spheres to dodecahedrons”, Chem. Commun. 47(37), 10332–10334 (2011). http://dx.doi.org/10.1039/c1cc13803k
  28. C. M. Hessel, M. R. Rasch, J. L. Hueso, B. W. Goodfellow, V. A. Akhavan, P. Puvanakrishnan, J. W. Tunnel and B. A. Korgel, “Alkyl passivation and amphiphilic polymer coating of silicon nanocrystals for diagnostic imaging”, Small 6(18), 2026–2034 (2010). http://dx.doi.org/10.1002/smll.201000825
  29. Z. Chen, Q. Wang, H. Wang, L. Zhang, G. Song, L. Song, J. Hu, H. Wang, J. Liu, M. Zhu and D. Zhao, “Ultrathin PEGylated W18O49nanowires as a new 980 nm-laser-driven photothermal agent for efficient ablation of cancer cells in vivo”, Adv. Mater. 25(14), 2095–2100 (2013). http://dx.doi.org/10.1002/adma.201204616
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