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Vol. 6 No. 2 (2014)

A Novel Photothermal Nanocrystals of Cu7S4 Hollow Structure for Efficient Ablation of Cancer Cells

https://doi.org/10.1007/BF03353781
Guosheng Song
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China
Linbo Han
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China
Weiwei Zou
Radiology Departments, Changzheng Hospital, Shanghai 200003, China
Zhiyin Xiao
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China
XiaoJuan Huang
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China
Zongyi Qin
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China
Rujia Zou
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China
Junqing Hu
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China

Corresponding Author: Junqing Hu

hu.junqing@dhu.edu.cn

Nano-Micro Letters, Vol. 6 No. 2 (2014), Article Number: 169-177

Abstract

Cu2-xS nanocrystals (NCs), characterized by low cost, low toxicity, high stability and high photothermal conversion efficiency, provide promising platforms as photothermal agents. Herein, a novel two-step synthesis has been developed for Cu7S4 nanocrystals with hollow structure using the as-prepared copper nanoparticles as starting a solid precursor followed by hot-injection of sulfide source.The Cu7S4 NCs exhibit intense absorption band at Near-infrared (NIR) wavelengths due to localized surface plasmon resonance (LSPR) mode, which can effectively convert 980 nm-laser energy into heat.Moreover, the localized high temperature created by Cu7S4 NCs under NIR irradiation could result in efficient photothermal ablation (PTA) of cancer cells in vivo, demonstrating a novel and promising photothermal nanomaterials.

Keywords

Semiconductor nanocrystals Near-infrared absorption Photothermal
Song, Guosheng, Linbo Han, Weiwei Zou, Zhiyin Xiao, XiaoJuan Huang, Zongyi Qin, Rujia Zou, and Junqing Hu. 2014. “A Novel Photothermal Nanocrystals of Cu7S4 Hollow Structure for Efficient Ablation of Cancer Cells”. Nano-Micro Letters 6 (2):169-77. https://doi.org/10.1007/BF03353781.
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