Bilirubin adsorption property of mesoporous silica and amine-grafted mesoporous silica
Corresponding Author: J. L. Shi
Nano-Micro Letters,
Vol. 1 No. 1 (2009), Article Number: 14-18
Abstract
Nephritic, hepatic and immune failures would lead to the overload of endogenous toxic molecules (e.g. bilirubin, cholic acid, uric acid, creatinine etc.) in human bodies. It is fatal in most cases and extracorporeal blood purification (ECBP) is powerful first-aid therapy. Adsorbents are key parts of ECBP apparatus. Mesoporous silicas should be promising candidates for these medical adsorbents, but there is no report about this. Herein, pure and amine-grafted mesoporous silicas have been applied to adsorb bilirubin, cholic acid, uric acid, creatinine and phenobarbital for the first time. These mesoporous materials show high adsorption capacities for bilirubin and uric acid in phosphate buffer solution (PBS). Effects of pore sizes, amine-modification, temperature and ionic strength on their bilirubin adsorption capacities have been studied in detail.
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- R. Guo, L. Y. Jia, H. Q. Feng and C. Y. Zou, Chin. J. Blood Purificat. 3, 43 (2004).
- A. E. Briglia, Semin. Dialysis. 18, 380 (2005).
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- Y. Yang, Y. T. Wang and W. A. Zhang, J. Appl. Polym. Sci. 99, 1264 (2006). doi:10.1002/app.22652
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- X. D. Feng, G. E. Fryxell, L. Q. Wang, A. Y. Kim, J. Liu and K. M. Kemner, Science 276, 923 (1997). doi:10.1126/science.276.5314.923
- L. X. Zhang, W. H. Zhang, J. L. Shi, Z. L. Hua, Y. S. Li and J. N. Yan, Chem. Commun. 2, 210 (2003). doi:10.1039/b210457a
- G. E. Fryxell and G. Z. Cao, Imperial College Press (2007).
- W. R. Zhao, J. L. Gu, L. X. Zhang, H. R. Chen and J. L. Shi, J. Am. Chem. Soc. 127, 8916 (2005). doi:10.1021/ja051113r
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- D. Y. Zhao, Q. S. Huo, J. Feng, B. F. Chmelka and G. D. Stucky, J. Am. Chem. Soc. 120, 6024 (1998). doi:10.1021/ja974025i
- H. Yoshitake, T. Yokoi and T. Tatsumi, Chem. Mater. 15, 1713 (2003). doi:10.1021/cm0218007
- L. X. Zhang, C. C. Yu, W. R. Zhao, Z. L. Hua, H. R. Chen, L. Li and J. L. Shi, J. Non-Cryst. Solids 353, 4055 (2007). doi:10.1016/j.jnoncrysol.2007.06.018
- F. Kleitz, S. H. Choi and R. Ryoo, Chem. Commun. 2136 (2003). doi:10.1039/b306504a
- C. T. Kresge, M. E. Eonowicz, W. J. Roth, J. C. Vartuli and J. S. Beck, Nature 359, 710 (1992). doi:10.1038/359710a0
- W. H. Zhang, J. L. Shi and H. R. Chen, Chem. Mater. 13, 648 (2001). doi:10.1021/cm000621r
- Y. H. Yu and B. L. He, React. Funct. Polym. 31, 195 (1996). doi:10.1016/1381-5148(96)00051-X
References
R. Guo, L. Y. Jia, H. Q. Feng and C. Y. Zou, Chin. J. Blood Purificat. 3, 43 (2004).
A. E. Briglia, Semin. Dialysis. 18, 380 (2005).
J. D. Zhang and Z. Yuan, Chin. Polym. Bull. 4, 25 (2006).
Z. Yang, S. Si and Y. Fung, Thin Solid Films 515, 3344 (2007). doi:10.1016/j.tsf.2006.09.018
M. C. Annesini, C. D. Carlo, V. Piemote and L. Turchetti, Biochem. Eng. J. 40, 205 (2008).
Y. Yang, Y. T. Wang and W. A. Zhang, J. Appl. Polym. Sci. 99, 1264 (2006). doi:10.1002/app.22652
J. L. Shi, Z. L. Hua and L. X. Zhang, J. Mater. Chem. 14, 795 (2004). doi:10.1039/b315861f
X. D. Feng, G. E. Fryxell, L. Q. Wang, A. Y. Kim, J. Liu and K. M. Kemner, Science 276, 923 (1997). doi:10.1126/science.276.5314.923
L. X. Zhang, W. H. Zhang, J. L. Shi, Z. L. Hua, Y. S. Li and J. N. Yan, Chem. Commun. 2, 210 (2003). doi:10.1039/b210457a
G. E. Fryxell and G. Z. Cao, Imperial College Press (2007).
W. R. Zhao, J. L. Gu, L. X. Zhang, H. R. Chen and J. L. Shi, J. Am. Chem. Soc. 127, 8916 (2005). doi:10.1021/ja051113r
Y. F. Zhu, J. L. Shi, W. H. Shen, X. P. Dong, J. W. Feng, M. L. Ruan and Y. S. Li, Angew. Chem. Int. Ed. 44, 5083 (2005). doi:10.1002/anie.200501500
D. Y. Zhao, Q. S. Huo, J. Feng, B. F. Chmelka and G. D. Stucky, J. Am. Chem. Soc. 120, 6024 (1998). doi:10.1021/ja974025i
H. Yoshitake, T. Yokoi and T. Tatsumi, Chem. Mater. 15, 1713 (2003). doi:10.1021/cm0218007
L. X. Zhang, C. C. Yu, W. R. Zhao, Z. L. Hua, H. R. Chen, L. Li and J. L. Shi, J. Non-Cryst. Solids 353, 4055 (2007). doi:10.1016/j.jnoncrysol.2007.06.018
F. Kleitz, S. H. Choi and R. Ryoo, Chem. Commun. 2136 (2003). doi:10.1039/b306504a
C. T. Kresge, M. E. Eonowicz, W. J. Roth, J. C. Vartuli and J. S. Beck, Nature 359, 710 (1992). doi:10.1038/359710a0
W. H. Zhang, J. L. Shi and H. R. Chen, Chem. Mater. 13, 648 (2001). doi:10.1021/cm000621r
Y. H. Yu and B. L. He, React. Funct. Polym. 31, 195 (1996). doi:10.1016/1381-5148(96)00051-X