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Vol. 4 No. 2 (2012)

Micro and Nanotechnology for Intracellular Delivery Therapy Protein

https://doi.org/10.1007/BF03353702
Dan Xu
School of Pharmacy, Shanghai Jiao Tong University, No. 800 Dongchuan Road, Shanghai 200240, China
Zhenhua Hu
School of Pharmacy, Shanghai Jiao Tong University, No. 800 Dongchuan Road, Shanghai 200240, China
Jing Su
School of Pharmacy, Shanghai Jiao Tong University, No. 800 Dongchuan Road, Shanghai 200240, China
Fei Wu
School of Pharmacy, Shanghai Jiao Tong University, No. 800 Dongchuan Road, Shanghai 200240, China
Weien Yuan
School of Pharmacy, Shanghai Jiao Tong University, No. 800 Dongchuan Road, Shanghai 200240, China

Corresponding Author: Weien Yuan

yuanweien@126.com

Nano-Micro Letters, Vol. 4 No. 2 (2012), Article Number: 118-123

Abstract

Proteins therapy is of great importance in the treatment of protein deficiency disease. Most human diseases are related to the malfunctioning of one or more proteins. The most effective and direct approach is protein therapy, which delivers the proteins into the target cell to replace the dysfunction protein and maintain the balance of organism. However, clinical application is frequently hampered by various biological barriers to their successful delivery. This review aims to discuss the recent advances about microparticles and nanoparticles fabricated using micro and nanotechnology for intracellular delivery therapy protein and give some suggestions about the promising delivery system.

Keywords

Intracellular delivery Protein Nanoparticle
Xu, Dan, Zhenhua Hu, Jing Su, Fei Wu, and Weien Yuan. 2012. “Micro and Nanotechnology for Intracellular Delivery Therapy Protein”. Nano-Micro Letters 4 (2):118-23. https://doi.org/10.1007/BF03353702.
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