Issue

Vol. 16 (2024)

A Skin-Inspired Self-Adaptive System for Temperature Control During Dynamic Wound Healing

https://doi.org/10.1007/s40820-024-01345-0
Yaqi Geng
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, 2999 North Renmin Road, Shanghai 201620, People’s Republic of China
Guoyin Chen
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, 2999 North Renmin Road, Shanghai 201620, People’s Republic of China
Ran Cao
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, 2999 North Renmin Road, Shanghai 201620, People’s Republic of China
Hongmei Dai
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, 2999 North Renmin Road, Shanghai 201620, People’s Republic of China
Zexu Hu
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, 2999 North Renmin Road, Shanghai 201620, People’s Republic of China
Senlong Yu
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, 2999 North Renmin Road, Shanghai 201620, People’s Republic of China
Le Wang
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, 2999 North Renmin Road, Shanghai 201620, People’s Republic of China
Liping Zhu
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, 2999 North Renmin Road, Shanghai 201620, People’s Republic of China
Hengxue Xiang
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, 2999 North Renmin Road, Shanghai 201620, People’s Republic of China
Meifang Zhu
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, 2999 North Renmin Road, Shanghai 201620, People’s Republic of China

Corresponding Author: Meifang Zhu

zhumf@dhu.edu.cn

Nano-Micro Letters, Vol. 16 (2024), Article Number: 152

Abstract

The thermoregulating function of skin that is capable of maintaining body temperature within a thermostatic state is critical. However, patients suffering from skin damage are struggling with the surrounding scene and situational awareness. Here, we report an interactive self-regulation electronic system by mimicking the human thermos-reception system. The skin-inspired self-adaptive system is composed of two highly sensitive thermistors (thermal-response composite materials), and a low-power temperature control unit (Laser-induced graphene array). The biomimetic skin can realize self-adjusting in the range of 35–42 °C, which is around physiological temperature. This thermoregulation system also contributed to skin barrier formation and wound healing. Across wound models, the treatment group healed ~ 10% more rapidly compared with the control group, and showed reduced inflammation, thus enhancing skin tissue regeneration. The skin-inspired self-adaptive system holds substantial promise for next-generation robotic and medical devices.


Highlights:
1 An interactive electronic system inspired by the temperature self-regulation of human skin.
2 Heat stimulation therapy and temperature monitoring during dynamic wound healing.
3 Mechanism of temperature self-regulation during dynamic wound healing.

Keywords

Thermo-reception Self-regulation Flexible electronic system Wound healing
Geng, Yaqi, Guoyin Chen, Ran Cao, Hongmei Dai, Zexu Hu, Senlong Yu, Le Wang, Liping Zhu, Hengxue Xiang, and Meifang Zhu. 2024. “A Skin-Inspired Self-Adaptive System for Temperature Control During Dynamic Wound Healing”. Nano-Micro Letters 16 (March):152. https://doi.org/10.1007/s40820-024-01345-0.
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