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Vol. 12 (2020)

Boosting Chemodynamic Therapy by the Synergistic Effect of Co-Catalyze and Photothermal Effect Triggered by the Second Near-Infrared Light

https://doi.org/10.1007/s40820-020-00516-z
Songtao Zhang
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences (CAS), Changchun 130022, People’s Republic of China
Longhai Jin
Department of Radiology, The Second Hospital of Jilin University, Changchun 130041, People’s Republic of China
Jianhua Liu
Department of Radiology, The Second Hospital of Jilin University, Changchun 130041, People’s Republic of China
Yang Liu
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences (CAS), Changchun 130022, People’s Republic of China
Tianqi Zhang
Department of Radiology, The Second Hospital of Jilin University, Changchun 130041, People’s Republic of China
Ying Zhao
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences (CAS), Changchun 130022, People’s Republic of China
Na Yin
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences (CAS), Changchun 130022, People’s Republic of China
Rui Niu
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences (CAS), Changchun 130022, People’s Republic of China
Xiaoqing Li
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences (CAS), Changchun 130022, People’s Republic of China
Dongzhi Xue
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences (CAS), Changchun 130022, People’s Republic of China
Shuyan Song
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences (CAS), Changchun 130022, People’s Republic of China
Yinghui Wang
CAS Key Laboratory of Design and Assembly of Functional Nanostructures, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, People’s Republic of China
Hongjie Zhang
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences (CAS), Changchun 130022, People’s Republic of China

Corresponding Author: Hongjie Zhang

hongjie@ciac.ac.cn

Nano-Micro Letters, Vol. 12 (2020), Article Number: 180

Abstract

In spite of the tumor microenvironments responsive cancer therapy based on Fenton reaction (i.e., chemodynamic therapy, CDT) has been attracted more attentions in recent years, the limited Fenton reaction efficiency is the important obstacle to further application in clinic. Herein, we synthesized novel FeO/MoS2 nanocomposites modified by bovine serum albumin (FeO/MoS2-BSA) with boosted Fenton reaction efficiency by the synergistic effect of co-catalyze and photothermal effect of MoS2 nanosheets triggered by the second near-infrared (NIR II) light. In the tumor microenvironments, the MoS2 nanosheets not only can accelerate the conversion of Fe3+ ions to Fe2+ ions by Mo4+ ions on their surface to improve Fenton reaction efficiency, but also endow FeO/MoS2-BSA with good photothermal performances for photothermal-enhanced CDT and photothermal therapy (PTT). Consequently, benefiting from the synergetic-enhanced CDT/PTT, the tumors are eradicated completely in vivo. This work provides innovative synergistic strategy for constructing nanocomposites for highly efficient CDT.




Highlights

1 The MoS2 nanosheets served as co-catalyst could reduce Fe3+ ions with lower Fenton reaction activity into the highly reactive Fe2+ ions, thereby boosting the production of hydroxyl radical (•OH) for high efficiency chemodynamic therapy (CDT).


2 The photothermal effect of MoS2 nanosheets motivated by second near-infrared light could further improve the treatment effectiveness by synergetic photothermal-enhanced CDT and photothermal therapy.



Keywords

Chemodynamic therapy Fenton reaction Co-catalysis Photothermal effect NIR II biowindows
Zhang, Songtao, Longhai Jin, Jianhua Liu, Yang Liu, Tianqi Zhang, Ying Zhao, Na Yin, Rui Niu, Xiaoqing Li, Dongzhi Xue, Shuyan Song, Yinghui Wang, and Hongjie Zhang. 2020. “Boosting Chemodynamic Therapy by the Synergistic Effect of Co-Catalyze and Photothermal Effect Triggered by the Second Near-Infrared Light”. Nano-Micro Letters 12 (September):180. https://doi.org/10.1007/s40820-020-00516-z.
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References
  1. R.L. Siegel, K.D. Miller, A. Jemal, Cancer statistics, 2019. CA Cancer J. Clin. 69(1), 7–34 (2019). https://doi.org/10.3322/caac.21551
  2. R.L. Siegel, K.D. Miller, A. Jemal, Cancer statistics, 2018. CA Cancer J. Clin. 68(1), 7–30 (2018). https://doi.org/10.3322/caac.21442
  3. H.J. Bonjer, E. Haglind, I. Jeekel, G. Kazemier, L. Pahlman et al., Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomised trial. Lancet Oncol. 6(7), 477–484 (2005). https://doi.org/10.1016/s1470-2045(05)70221-7
  4. E. Kapiteijn, C.A.M. Marijnen, I.D. Nagtegaal, H. Putter, W.H. Steup et al., Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N. Engl. J. Med. 345(9), 638–646 (2001). https://doi.org/10.1056/NEJMoa010580
  5. D. Cunningham, W.H. Allum, S.P. Stenning, J.N. Thompson, C.J.H. Van de Velde et al., Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. N. Engl. J. Med. 355(1), 11–20 (2006). https://doi.org/10.1056/NEJMoa055531
  6. H.I. Scher, K. Fizazi, F. Saad, M.-E. Taplin, C.N. Sternberg et al., Increased survival with enzalutamide in prostate cancer after chemotherapy. N. Engl. J. Med. 367(13), 1187–1197 (2012). https://doi.org/10.1056/NEJMoa1207506
  7. Z. Tang, H. Zhang, Y. Liu, D. Ni, H. Zhang et al., Antiferromagnetic pyrite as the tumor microenvironment-mediated nanoplatform for self-enhanced tumor imaging and therapy. Adv. Mater. 29(47), 1701683 (2017). https://doi.org/10.1002/adma.201701683
  8. H. Lin, Y. Chen, J. Shi, Fenton re nanoparticle-triggered in situ catalytic chemical reactions for tumour-specific therapy. Chem. Soc. Rev. 47(6), 1938–1958 (2018). https://doi.org/10.1039/c7cs00471k
  9. M.I. Litter, M. Slodowicz, An overview on heterogeneous fenton and photofenton reactions using zerovalent iron materials. J. Adv. Oxid. Technol. 20(1), 160164 (2017). https://doi.org/10.1515/jaots-2016-0164
  10. Y. Wang, K. Qi, S. Yu, G. Jia, Z. Cheng et al., Revealing the intrinsic peroxidase-like catalytic mechanism of heterogeneous single-atom Co–MoS2. Nano Micro Lett. 11(1), 102 (2019). https://doi.org/10.1007/s40820-019-0324-7
  11. C. Yang, M. Zhou, C. He, Y. Gao, S. Li et al., Augmenting intrinsic fenton-like activities of mof-derived catalysts via n-molecule-assisted self-catalyzed carbonization. Nano Micro Lett. 11(1), 87 (2019). https://doi.org/10.1007/s40820-019-0319-4
  12. M. Huo, L. Wang, Y. Chen, J. Shi, Tumor-selective catalytic nanomedicine by nanocatalyst delivery. Nat. Commun. 8(1), 357 (2017). https://doi.org/10.1038/s41467-017-00424-8
  13. W. Wang, Y. Jin, Z. Xu, X. Liu, S.Z. Bajwa, W.S. Khan, H. Yu, Stimuli-activatable nanomedicines for chemodynamic therapy of cancer. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 12(4), e1614 (2020). https://doi.org/10.1002/wnan.1614
  14. Z. Tang, Y. Liu, M. He, W. Bu, Chemodynamic therapy: Tumour microenvironment-mediated fenton and fenton-like reactions. Angew. Chem. Int. Ed. 58(4), 946–956 (2019). https://doi.org/10.1002/anie.201805664
  15. S. Wang, G. Yu, Z. Wang, O. Jacobson, L.S. Lin et al., Enhanced antitumor efficacy by a cascade of reactive oxygen species generation and drug release. Angew. Chem. Int. Ed. 58(41), 14758–14763 (2019). https://doi.org/10.1002/anie.201908997
  16. Y. Liu, J. Wu, Y. Jin, W. Zhen, Y. Wang et al., Copper (i) phosphide nanocrystals for in situ self-generation magnetic resonance imaging-guided photothermal-enhanced chemodynamic synergetic therapy resisting deep-seated tumor. Adv. Funct. Mater. (2019). https://doi.org/10.1002/adfm.201904678
  17. Y. Liu, W. Zhen, Y. Wang, J. Liu, L. Jin et al., One-dimensional Fe2P acts as a fenton agent in response to NIR ii light and ultrasound for deep tumor synergetic theranostics. Angew. Chem. Int. Ed. 58(8), 2407–2412 (2019). https://doi.org/10.1002/anie.201813702
  18. L. Xu, J. Wang, Magnetic nanoscaled Fe3O4/CeO2 composite as an efficient fenton-like heterogeneous catalyst for degradation of 4-chlorophenol. Environ. Sci. Technol. 46(18), 10145–10153 (2012). https://doi.org/10.1021/es300303f
  19. M. Xing, W. Xu, C. Dong, Y. Bai, J. Zeng et al., Metal sulfides as excellent co-catalysts for H2O2 decomposition in advanced oxidation processes. Chem 4, 1359–1372 (2018). https://doi.org/10.1016/j.chempr.2018.03.002
  20. X. Nie, L. Xia, H.L. Wang, G. Chen, B. Wu et al., Photothermal therapy nanomaterials boosting transformation of Fe(iii) into Fe(ii) in tumor cells for highly improving chemodynamic therapy. ACS Appl. Mater. Interfaces 11(35), 31735–31742 (2019). https://doi.org/10.1021/acsami.9b11291
  21. L. Zhang, S.S. Wan, C.X. Li, L. Xu, H. Cheng, X.Z. Zhang, An adenosine triphosphate-responsive autocatalytic fenton nanoparticle for tumor ablation with self-supplied H2O2 and acceleration of Fe(iii)/Fe(ii) conversion. Nano Lett. 18(12), 7609–7618 (2018). https://doi.org/10.1021/acs.nanolett.8b03178
  22. T. Liu, S. Shi, C. Liang, S. Shen, L. Cheng et al., Iron oxide decorated MoS2 nanosheets with double pegylation for chelator-free radio labeling and multimodal imaging guided photothermal therapy. ACS Nano 9(1), 950–960 (2015). https://doi.org/10.1021/nn506757x
  23. J. Yu, W. Yin, X. Zheng, G. Tian, X. Zhang et al., Smart MoS2/Fe3O4 nanotheranostic for magnetically targeted photothermal therapy guided by magnetic resonance/photoacoustic imaging. Theranostics 5(9), 931–945 (2015). https://doi.org/10.7150/thno.11802
  24. S.S. Chou, B. Kaehr, J. Kim, B.M. Foley, M. De et al., Chemically exfoliated MoS2 as near-infrared photothermal agents. Angew. Chem. Int. Ed. 52(15), 4160–4164 (2013). https://doi.org/10.1002/anie.201209229
  25. C. Liu, J. Chen, Y. Zhu, X. Gong, R. Zheng et al., Highly sensitive MoS2-indocyanine green hybrid for photoacoustic imaging of orthotopic brain glioma at deep site. Nano-Micro Lett. 10(3), 48 (2018). https://doi.org/10.1007/s40820-018-0202-8
  26. W. Yin, J. Yu, F. Lv, L. Yan, L.R. Zheng, Z. Gu, Y. Zhao, Functionalized nano-MoS2 with peroxidase catalytic and near-infrared photothermal activities for safe and synergetic wound antibacterial applications. ACS Nano 10(12), 11000–11011 (2016). https://doi.org/10.1021/acsnano.6b05810
  27. F. Cao, L. Zhang, H. Wang, Y. You, Y. Wang et al., Defect-rich adhesive nanozymes as efficient antibiotics for enhanced bacterial inhibition. Angew. Chem. Int. Ed. (2019). https://doi.org/10.1002/anie.201908289
  28. Z. Wang, Y. Ju, Z. Ali, H. Yin, F. Sheng et al., Near-infrared light and tumor microenvironment dual responsive size-switchable nanocapsules for multimodal tumor theranostics. Nat. Commun. 10(1), 4418 (2019). https://doi.org/10.1038/s41467-019-12142-4
  29. S. Aktaş, S.C. Thornton, C. Binns, L. Lari, A. Pratt, R. Kröger, M.A. Horsfield, Control of gas phase nanoparticle shape and its effect on MRI relaxivity. Mater. Res. Express 2(3), 035002 (2015). https://doi.org/10.1088/2053-1591/2/3/035002
  30. B. Tang, W.-L. Li, Y. Chang, B. Yuan, Y. Wu et al., A supramolecular radical dimer: High-efficiency NIR-ii photothermal conversion and therapy. Angew. Chem. Int. Ed. (2019). https://doi.org/10.1002/anie.201910257
  31. X. Wu, Y. Suo, H. Shi, R. Liu, F. Wu et al., Deep-tissue photothermal therapy using laser illumination at NIR-iia window. Nano-Micro Lett. 12(1), 38 (2020). https://doi.org/10.1007/s40820-020-0378-6
  32. J.-L. Chen, H. Zhang, X.-Q. Huang, H.-Y. Wan, J. Li et al., Antiangiogenesis-combined photothermal therapy in the second near-infrared window at laser powers below the skin tolerance threshold. Nano Micro Lett. 11(1), 93 (2019). https://doi.org/10.1007/s40820-019-0327-4
  33. W. Feng, X. Han, R. Wang, X. Gao, P. Hu et al., Nanocatalysts-augmented and photothermal-enhanced tumor-specific sequential nanocatalytic therapy in both NIR-i and NIR-ii biowindows. Adv. Mater. 31(5), e1805919 (2019). https://doi.org/10.1002/adma.201805919
  34. W.P. Li, C.H. Su, Y.C. Chang, Y.J. Lin, C.S. Yeh, Ultrasound-induced reactive oxygen species mediated therapy and imaging using a fenton reaction activable polymersome. ACS Nano 10(2), 2017–2027 (2016). https://doi.org/10.1021/acsnano.5b06175
  35. A. Dong, X. Ye, J. Chen, Y. Kang, T. Gordon, J.M. Kikkawa, C.B. Murray, A generalized ligand-exchange strategy enabling sequential surface functionalization of colloidal nanocrystals. J. Am. Chem. Soc. 133(4), 998–1006 (2011). https://doi.org/10.1021/ja108948z
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